What are the stages of development of teeth, and what are some of the problems that can interfere

Teeth form in concert with a series of epithelial-mesenchymal
interactions. Histologically, developing teeth
pass through initiation, bud, cap, bell, crown formation,
and root formation stages. Genetic defects affecting the
earliest stages of tooth development lead to familial tooth
agenesis. Numerous syndromes have hypodontia as a feature.
Defects in AXIN2 (part of the Wnt signaling system)
and the transcription factor genes MSX1 and PAX9
cause different patterns of familial tooth agenesis that
most severely affect the molar regions. D’Souza (Baylor
College of Dentistry) and Klein (University of California)
review the developmental opposite of hypodontia (supernumerary
teeth) in their paper, Unraveling the Molecular
Mechanisms That Lead to Supernumerary Teeth in Mice
and Men.

Source:

Molecular Evolution and Genetic Defects of Teeth, Cells Tissues Organs, 2007

Development stages of teeth and problems of dental development

What are the stages of development of teeth, and what are some of the problems that can interfere

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