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Does testosterone have a role in muscle development

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Does testosterone have a role in muscle development?
Testosterone is a potent stimulator of muscle protein synthesis (8, 29, 30). As previously stated, a hormone receptor complex must be present for the action of testosterone to occur. These complexes may occur in the cytosol and then translocate to the nucleus (65, 69), or they may occur directly in the nucleus itself. Regardless of the location, activation of the receptor-hormone complex will increase mRNA and DNA synthesis. This increase in action will lead to increased protein accretion via increased intramuscular amino aciduptake (3). Testosterone also possesses anticatabolic properties within skeletal muscle. Inhibition of muscle glycogen breakdown (5, 33) and displacement of glucocorticoidvia attachment to its receptor (66) are two powerful mechanisms of skeletal muscle protein retention.

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